ct 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T27093	CT-1	CT 1	p53
	CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.		p53
T5S0636	Citric acid	Citro,Citretten	Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
	1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T79262	SSI-4		Stearoyl-CoA Desaturase (SCD)
	SSI-4 is a Stearoyl CoA desaturase 1 (SCD1) inhibitor that can be labeled with carbon-11 (11C) for use as a ligand in small animal in vivo PET/CT imaging studies of SCD1 [1].		Stearoyl-CoA Desaturase (SCD)
T81461	Pidilizumab	CT-011,MDV9300	PD-1/PD-L1
	Pidilizumab (CT-011), a humanized IgG1κ anti-PD-1 monoclonal antibody, serves as a DLL1 antagonist with potential applications in researching hematologic malignancies [1].		PD-1/PD-L1
T78153	PSMA I&T		Others
	PSMA I&T, a potent inhibitor of prostate-specific membrane antigen (PSMA), facilitates SPECT/CT imaging and radionuclide research in prostate cancer (PCa) [1].		Others
T74878	Enzyme-IN-1
	Enzyme-IN-1 (compound 1), a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases, specifically targets and inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. This compound may possess pot...
T77094	Navivumab
	Navivumab (CT-P23) is a monoclonal antibody targeting the hemagglutinin HA of the influenza A virus, effectively neutralizing strains H1, H2, H5, and H9 by binding to the HA2 stem fusion domain [1].
T80220	OK2		EGFR
	OK2, a specific inhibitor of the CCN2/EGFR interaction, effectively disrupts this interaction by binding to the CT domain of CCN2. It holds potential for use in research pertaining to kidney fibrosis and chronic kidney d...		EGFR
T77009	Firivumab
	Firivumab (CT-P22; CT120), a human IgG1 monoclonal antibody targeting influenza A virus hemagglutinin (Anti-IAV HA), demonstrates neutralization capabilities against multiple strains including H1N1, H5N1, H6N1, H6N2, H8N...
T75820	Gap19 TFA
	Gap19 TFA is a selective and potent blocker of connexin 43 (Cx43) hemichannels, originating from nine amino acids within the Cx43 cytoplasmic loop (CL). It operates by hindering intramolecular interactions between the C-...
T76851	Regdanvimab
	Regdanvimab (CT-P59) is a human monoclonal antibody designed to target the receptor-binding domain of the SARS-CoV-2 spike protein, thereby inhibiting the virus's ability to enter cells by blocking its interaction with t...
T77148	Pegdinetanib
	Pegdinetanib (BMS-844203; CT-322) is a selective inhibitor targeting VEGFR-2 (VEGFR), exhibiting dissociation constants (Kd) of 11 nM and 250 nM and half-maximal inhibitory concentrations (IC50) of 16 nM and 240 nM for h...
T36848	Combretastatin A-1	Combretastatin A1	Akt , Microtubule Associated
	Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and...		Akt , Microtubule Associated